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Plexr Omnia

An innovative, corrective medical-aesthetic total method. Indications such as sagging skin, wrinkles and subcutaneous fat deposits are thoroughly treated by Plexr Omnia system methods without the need for cutting, stitching and injecting foreign substances.

The concept consists of several synergistic techniques with which various small and extensive treatments are applied:


Plexr - Plasma Exeresis skin reduction by sublimation


Collagen Shaping lifting and filling by moving your own collagen


LipoPlexr lipolytic fat treatment


EndoPlexr a complex hybrid method for strengthening and lifting

What is Plexr Omnia

THE NEW FRONTIER OF SOFT SURGERY IN ONE MEDICAL DEVICE - PLEXR VECRON From decades of experience in the field of aesthetic medicine, GMV offers a new treatment protocol for a complete and completely natural face lift, through the combination of 3 different technologies: Plexr, Needle Shaping and OFF. Plexr Vecron device includes: Plexr, Needle Shaping, OFF, Carboxytherapy. Indicated for: sagging and excess skin, subcutaneous fat zones and general signs of skin aging.

Benefits of Plexr Omnia System

Targeted precision corrective treatments​

A natural and absolutely safe method to achieve a rejuvenated appearance

Long-term preservation of the results

Total skin improvement

Slowing down the natural aging process

Scientific Validations

“Carboxytherapy is an effective technique of treatment of cellulite
in the buttocks region and posterior thighs of healthy women.”

[Ramalho Pianez L, Silva Custódio F, Michelini Guidi R, Nunes de Freitas
J, Sant’Ana E. Effectiveness of carboxytherapy in the treatment of
cellulite in healthy women: a pilot study. Clinical, Cosmetic and
Investigational Dermatology]

“The two innovative methods (Needle Shaping, O.F.F.) open up new
horizons in aesthetic medicine and bloodless surgery… Thanks to
their excellent results, the patient recommends the treatments in
his wider social circle and do not hesitate to make other cosmetic
procedures (non surgical) because he/She does not face the fear
of surgery.”

[Tsioumas G S, Chorozidis I, Papapostolou A. The Efficiency Of
Vibrance (Needle Shaping) And O.F.F (Non Surgical Dermal Ablative
Treatment) On Body Reshaping. Pinnacle Medicine & Medical

“Unlike contemporary physical methods that affect all tissue
components, Pulsed Electric Fields (PEF) is an intervention
at the cellular level, which precisely targets cell membranes
through electroporation without affecting the extracellular matrix

[Golberg A, et al. Skin Rejuvenation with Non-Invasive Pulsed Electric
Fields. Scientific Reports]

“The technique of manual lymphatic drainage (MLD) is one of
the main pillars of the treatment of lymphedema, because its
movements help lymphatic circulation”

[Schonvvetter B, Soares JLM, Bagatin E. Longitudinal evaluation of
manual lymphatic drainage for the treatment of gynoid lipodystrophy.
An Bras Dermatol.]

Technical Features

Plexr Vecron Omnia - Technical features table for OFF, Needle Shaping and Carbomax
THE NEW FRONTIER OF SOFT SURGERY IN ONE MEDICAL DEVICE - PLEXR VECRON From decades of experience in the field of aesthetic medicine, GMV offers a new treatment protocol for a complete and completely natural face lift, through the combination of 3 different technologies: Plexr, Needle Shaping and OFF. Plexr Vecron device includes: Plexr, Needle Shaping, OFF, Carboxytherapy. Indicated for: sagging and excess skin, subcutaneous fat zones and general signs of skin aging.
Science book with microscope

A unique medical device that combines the principles of physics and biology to provide the doctor with all the instruments for non-invasive surgery treatments


  • 2 technologies based on the fundamentals of electrophysiology

  • 1 technology that uses biochemical mechanisms

  • Scientifically validated technologies 1, 2, 3 and tested over the years on hundreds of patients with excellent results

  • Immediate and progressive results over time

  • User friendly software: the operator is guided throughout the treatment

  • Pre-set work protocols

Collagen Shaping

What is Needle Shaping

Needle Shaping is based on the principle of applicating regenerative electrostimulating
micro-currents which, combined with the principles of acupuncture, allow to perform bioregeneration, lifting and modeling of volumes in a completely natural and autologous way (that’s why the treatment is called Collagen Shaping). This regenerative technique allows to ameliorate and increase the
duration of the effect of threads or injectable and non-injectable gels. In fact, introducing these products in a healthy and hydrated skin, empower a better and long-lasting result.

How does it work


A microscopic self-transplantation of dermal fibers by traction is performed using a particular extremely thin needle crossed by micro-currents. The doctor
chooses the traction line to be solicited or the volume to be modelled and applies the needles to the cardinal points. The needle crossed by microcurrents is rotated and the fibers are hooked to it. In this way, the fibers are pulled towards the insertion point. The donor structures, thinned, will resume the initial volumes in the next twenty-eight days, while the reconstructed part reaches the final volume after about seven days, to maintain it for a long time.

The bioregeneration of the fibers and the stimulation of the SMAS, with the consequent lifting and modeling effect, is obtained in an autologous way through mechanical and electrical stimulation. The results are immediately visible, and they improve over time. The quality of the skin is increased on the surface (immediately visible) and mostly in the dermal layer. So, the regenerative effect allows cross-linked and non-crosslinked hyaluronic acid, grow factors, threads to have a better and more long-lasting effects.
The patient who undergoes the treatment does not perceive any discomfort as the current is extremely low and delivered only for a few seconds.


  • Correction of facial hypovolumeters

  • Increasing lip volume

  • Correction of expression lines

  • Scars treatment

  • Saline deprivation of the subcutaneous tissue

  • Collagen regeneration

  • Biostimulation of the face

  • Autologous virtual traction lines

Needle Shaping Techniques by Tsioumas Sotirios MD
Needle Shaping  - results
Needle Shaping on Upper and Under Arm

Lipo Plexr

What is O.F.F.

OFF is a device that generates a fixed RF frequency sine wave of about 1230kHz with a fractionable flow, able to transfer concentrated energy through a handpiece equipped with a sterile and disposable needle. Through of it is possible to perform two different treatments: microlipolysis (named Lipo Plexr) and superficial vascular lesion removal (V Plexr).

How does it work

The produced sinusoidal wave is transformed into fractional heat because of Joule effect, due to the Joule effect which can be used for non-invasive selective micro lipolysis treatments - directed in the subcutaneous fatty region - and the removal of small angiomas, capillaries and telangiectasias. These sine waves are programmable in order to obtain different results on different tissues also according to the method of application.

Removal of superficial vascular lesions – V Plexr (angiomas, capillaries, telangiectasias): the wave must be applied from outside the skin by putting
the needle in contact with the skin without inserting it into it. Through the fractional heat, the elastic fibers of the vessel will contract, allowing the vessel
walls to attach to each other and collapse, removing the blood content inside.
Micro-lipoplasty - Lipo Plexr (Jaw, eye bags, fat deposit): the technique of using Lipo Plexr provides for the presence of normal acupuncture needles that are fixed in the tissues until reaching the localized adipose tissue to be eliminated for hyperthermia inducing the programmed adipocytic apoptosis. The tip of the OFF it will be approached to the needles without entering the underlying skin and without causing damage to the overlying skin.


  • The adipose tissue allows to treat limited distribution of heat that totally involves hyperthermia. This selective tissue induced by selective and time fractionated - Lipo Plexr: dissolution of adipose harmonizing effect. The fat is returned to areas of adipose deposits, obtaining a the cellular state so that it also becomes bioregenerative using its own stem cells.

  • V(ascular) Plexr: Removal of capillaries, angiomas and superficial telangiectasias, especially on the face.

OFF Demonstration near nose and under eyes
OFF Demonstration of treatment on cheeks



Carboxytherapy is the use of carbon dioxide in the gaseous state for therapeutic purposes. This technique originated at the beginning of the last century in France, but the term was first introduced by Luigi Parassoni in 1995 during the XVI National Congress of the Italian Society of Aesthetic Medicine.

How does it work

The treatment is performed through the Vecron device connected to a cylinder containing medical CO2. The device is connected to a flow tube with a small needle that is inserted into the area to be treated: when everything is well positioned, the device is activated and the gas is injected into the subcutaneous tissue. The effects that carbon dioxide generates within our body, which have been the subject of numerous studies over the years, can be summarized as: a rehabilitation treatment to rebalance microcirculation (vasodilation and neoangiogenesis) and better oxygenate the tissues; an increase in lipolysis; a stimulus to the proliferation and activation of fibroblasts (the cells responsible
for the production of collagen); an increase in the oxidative processes of fatty acids present in the body.
It is a safe treatment: there are no side effects even at the highest doses (2-3 liters); there are no changes in blood pressure; there is no overload of the emunctors such as the liver or kidney; nitrogen embolisms do not occur, as can happen, for example, with oxygen-ozone therapy. Sometimes bruises can occur on the treated area, which disappear in a short time.


This biochemical mechanism is applied in
numerous specific therapeutic indications:


  • Localized adiposity

  • Diffuse lipomatosis

  • So-called “cellulite”

  • Psoriasis

  • Striae Distensae (stretch marks)

  • Skin laxity

  • Skin aging

  • Venous insufficiency

  • “Restless Leg” syndrome

  • Acrocyanosis

  • Peripheral arteriopathies

  • Reynaud phenomenon

  • Sexual impotence on a vascular basis

  • Alopecia

  • Treatment of skin ulcers

  • Rejuvenation of the female external genital tissues

Carbomax, before and after treatments


Video Resources

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Histological & Microscopical Evaluation

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Histological evaluation by light microscopy of biopsies taken before and after needle shaping treatment. (A and C) Skin samples before (panel A, ×25 magnification; panel C, ×100 magnification) and (B and D) after needle shaping treatment (panel B, ×25 magnification; panel D, ×100 magnification) were stained with trichrome staining (most significant micrographs are shown). Changes in matrix organization are indicated by arrows. The images depicting tissues after the treatment (B and D) demonstrated a more compact dermis, with a healthy matrix network. Specifically, collagen fibers are larger and thicker with a more ordered alignment of fibers of the treated skin as compared to the images obtained before treatment (A and C).

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Evaluation by scanning electron microscopy (SEM). Skin specimens were coated with gold and viewed using a scanning electron microscope at different magnifications before (A and C) and after (B and D) needle shaping treatment were (most significant micrographs shown).

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Evaluation by scanning electron microscopy (SEM) (most significant micrographs are shown). Skin specimens coated with gold (A) before and (B) after needle shaping treatment were viewed using a scanning electron microscope.

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